Key features and details | |
Cat. No. | MABL-1613 |
Name | Anti-FLNB mAbs |
Clone No. | AFD- SH7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | BLI, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for FLNB. FLNB is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskeletal network, to control and guide proper skeletal development. |
Alternative Name | Fh1; FLN-B; filamin B; Filamin-B; ABP-278; ABP-280 homolog; Actin- binding-like protein; Beta-filamin; Filamin homolog 1; Filamin-3; Thyroid autoantigen; Truncated actin- binding protein; Truncated ABP |
UniProt | O75369 |
Immunogen | The original antibody was generated by immunizing mice with FLNB antigen. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis. The binding kinetics of the antibody to the full length FLNA protein was measured by BLI (Kd= 1 nM) (WO2018085441A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
