Key features and details | |
Cat. No. | MABL-1642 |
Name | Anti-Gal/GalNAc Lectin from E. histolytica mAbs |
Clone No. | AFD- CD33-LA22 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Blocking, SPR, ELISA |
Species Reactivity | Entamoeba histolytica |
Basic Information | |
Specificity | The antibody binds with a Kd of 3.51 nM. |
Alternative Name | |
UniProt | C4LTM0 |
Immunogen | Peripheral Lymphocytes of an asymptomatic E. histolytica cyst passer. |
Application Notes | This antibody binds to E. histolytica Gal/GalNAc lectin, which is a multifuctional virulence factor which is involved in adherence, cytolysis, invasion, resistance to lysis by complemenet and encystment. The antibody blocks the lectin. |
Antibody First Published | Tachibana et al. VH3 gene usage in neutralizing human antibodies specific for the Entamoeba histolytica Gal/GalNAc lectin heavy subunit. Infection and Immunology 2003; 71(8):4313- 4319 PMID:12874307 |
Note on publication | Describes the generation of novel antibodies against amoebean antigens and shuffling of heavy- and light chains to optimise antigen-binding affinities. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
