Key features and details | |
Cat. No. | MABL-1645 |
Name | Anti-Galectin 9 mAbs |
Clone No. | AFD-2E 12 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | therapeutic, WB, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for human Gal-9. |
Alternative Name | Galectin-9; Gal-9; LGALS9; Ecalectin; Tumor antigen HOM-HD-21 |
UniProt | O00182 |
Immunogen | The original antibody was generated by immunizing BALB/c mice with a recombinant c- terminus galectin-9 (residues 191 to 355 of the galectin-9 long isoform). |
Application Notes | The binding of the original format of this antibody to c-terminus Gal-9 was assessed via ELISA. This antibody detected Gal-9 in a WB assay (Barjon et al., 2012; PMID: 22805533). An scFv-CAR version of this antibody with therapeutic potential was developed and described (US20230295564A1). |
Antibody First Published | Barjon et al. A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses. Infect Agent Cancer. 2012 Jul 17;7(1):16. PMID:22805533 |
Note on publication | The original publication presents the development of monoclonal antibodies targeting galectin-9. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |