Key features and details | |
Cat. No. | MABL-1653 |
Name | Anti-Ganglioside GD3 mAbs |
Clone No. | AFD- R24 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IHC-P, FC, IF, IHC-Fr |
Species Reactivity | Human |
Basic Information | |
Specificity | Recognises GD3, a prominent ganglioside of human melanoma, melanocytes and other cells of neuroectodermal origin. It furthermore recognises strocytes, certain groups of neurons in the brain, cells in the parotid, adrenal medulla and pancreatic islets. |
Alternative Name | d18:1/20:0 |
UniProt | |
Immunogen | SK-MEL-28 Melanoma cell line. |
Application Notes | |
Antibody First Published | Kaminski et al. The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains. J Biol Chem. 1999 Feb 26;274(9):5597-604. PMID:10026176 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
