Key features and details | |
Cat. No. | MABL-1676 |
Name | Anti-Genome polyprotein, Capsid protein VP3, Virion protein 3 mAbs |
Clone No. | AFD- VHH 10E |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | SPR |
Species Reactivity | Poliovirus type 1 |
Basic Information | |
Specificity | This antibody is specific for the VP3 protein from the genome polyprotein of the poliovirus. |
Alternative Name | Genome polyprotein; Capsid protein VP3; Virion protein 3 |
UniProt | P03300 |
Immunogen | The original antibody was raised by immunizing a dromedary with poliovirus type 1 Sabin strain. |
Application Notes | The structure of the original antibody was determined using cryo-EM (Strauss et al., 2017; PMID：27852863). The binding strength of the original antibody to poliovirus antigens was determined using surface plasmon resonance (Thys et al., 2011; PMID：21371506). |
Antibody First Published | Thys et al. In vitro antiviral activity of single domain antibody fragments against poliovirus Antiviral Res. 2010 Aug;87(2)：257-64 PMID：20566349 |
Note on publication | The original paper aimed to determine whether VHHs inhibit wild-type and vaccine strains of poliovirus type 1. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
