Key features and details | |
Cat. No. | MABL-1752 |
Name | Anti-GXM mAbs |
Clone No. | AFD-3E 5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, IHC |
Species Reactivity | Cryptococcus neoformans |
Basic Information | |
Specificity | This antibody is specific for GMX from Cryptococcus neoformans. |
Alternative Name | Glucuronoxylomannan |
UniProt | |
Immunogen | This antibody was raised by immunizing mice with GXM-TT. |
Application Notes | ELISA was preformed on CNPS-A using the murine version of this antibody (Mukherjee et al, 1993; pmid:8459205). This antibody was used for immunohistochemistry on lung tissue from mice infected with strains 24067 of C. neoformans. To determine the ability of antibodies to protect against pulmonary fungal pathogens (Feldmesser and Casadevall, 1997; pmid:8992996). |
Antibody First Published | Mukherjee et al. Molecular characterization of the humoral responses to Cryptococcus neoformans infection and glucuronoxylomannan-tetanus toxoid conjugate immunization. J Exp Med. 1993 Apr 1;177(4):1105-16. PMID:8459205 |
Note on publication | The molecular characteristics of the humoral immune response to a serotype A Cryptococcus neoformans infection were compared with the response elicited by a cryptococcal glucuronoxylomannan-tetanus toxoid (GXM-TT) conjugate. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
