Anti-HLA class II mAbs

Cat. No.

MABL-1848

Name

Anti-HLA class II mAbs

Clone No.

AFD- F3.3

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, FC

Species Reactivity

Human

Basic Information

Specificity

 Recognising anti-class II HLA   molecules.

Alternative Name

 HLA-DR; HLA class II related epitope

UniProt

Immunogen

Application Notes

This antibody has been show to   work by flow-cytometry and western blot. Dechant et al (PMID: 12393717) used   a human IgA2-chimeric version of this antibody to study IgA-mediated cell   killing.

Antibody First Published

Elsässer D, Valerius T, Repp R, Weiner GJ, Deo Y, Kalden JR, van de Winkel JG, Stevenson GT, Glennie MJ, Gramatzki M. HLA class II as potential target antigen on malignant B cells  for therapy with bispecific antibodies in combination with granulocyte   colony-stimulating factor. Blood. 1996 May 1;87(9):3803-12. PMID:8611706

Note on publication

 Describes the preparation and   characterisation of anti human HLA class II antibody by of ADCC of G-CSF   primed PMN expressing in the presence of F3.3 to HLA class II related epitope   (HLA- DR).

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store   at - 20⁰C.