Anti-Human Creatine Kinase-MM mAbs

Cat. No.

MABL-1901

Name

Anti-Human Creatine   Kinase-MM mAbs

Clone No.

AFD- MAK33

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA

Species Reactivity

Human

Basic Information

Specificity

The antibody binds specifically to the human creatine-kinase-MM subtype (and not the the MB or BB subtype).

Alternative Name

CK-MM

UniProt

P06732

Immunogen

Human creatine-kinase-MM in Al(OH)3.

Application Notes

This antibody binds to human muscle creatine-kinase-MM, an enzyme that catalyzes the conversion of creatine and ATP to phosphocreatine and ADP, generating an ATP-buffer in the muscle. The antibody   blocks CK-MM activity by 80%.

Antibody First   Published

Buckel et al. Cloning and nucleotide   sequence of heavy- and light-chain cDNAs from a creatine-kinase specific   monoclonal antibody Gene 1987; 51:13-19 PMID:3110009

Note on publication

Describes the generation of a monoclonal antibody   directed against the human creatine kinase M-subunit.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.