Key features and details | |
Cat. No. | MABL-1931 |
Name | Anti-IFN gamma mAbs |
Clone No. | AFD- A4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Biacore, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds to human Interferon gamma |
Alternative Name | IFNG; Interferon gamma; Immune interferon; IFN-gamma |
UniProt | P01579 |
Immunogen | 2D-PAGE gel isolated human IFN gamma from lysate of human melanoma COLO-38 cells. |
Application Notes | The antibody binds specifically to IFN gamma, a dimerised soluble cytokine member of the type II class of interferons synthesised by activated T-lymphocytes and natural killer (NK) cells. . IFNγ plays a role in both the innate and adaptive immune responses, and is important in the activation of macrophages, induces the expression of MHC class I molecules, and has antiviral and immunoregulatory activities. |
Antibody First Published | Pini et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem. 1998 Aug 21;273(34):21769-76. PMID:9705314 |
Note on publication | Describes generation, using phage display, of antibodies with subnanomolar affinity against markers of angiogenesis. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
