Key features and details | |
Cat. No. | MABL-1933 |
Name | Anti-IFN gamma mAbs |
Clone No. | AFD- D9D10 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, Block, ELISA, FC |
Species Reactivity | Baboon, Human |
Basic Information | |
Specificity | Binds human interferon-gamma, a dimerized soluble cytokine that is the only member of the type II class of interferons. Cross reacts with baboon IFN gamma. |
Alternative Name | Interferon gamma; Immune interferon; IFN-gamma; IFNG |
UniProt | P01579 |
Immunogen | FPLC-purified natural human IFN-y. Refer to the original article [PMID: 3114127] |
Application Notes | This antibody can be used to detect both native and recombinant intereferon gamma (IFNg). It is reported only to bind to the functional, dimeric form of IFNg. |
Antibody First Published | Froyen G, Ronsse I, Billiau A. Bacterial expression of a single-chain antibody fragment (SCFV) that neutralizes the biological activity of human interferon-gamma. Mol Immunol. 1993 Jun;30(9):805-12. PMID:8321246 |
Note on publication | Describes the preparation anti human interferon gamma antibody by D9D10 hybridoma seqencing (VH and VK) and identified using ELISA and SDS-PAGE (for neuralisation of antiviral activity) techniques. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |