Key features and details | |
Cat. No. | MABL-2014 |
Name | Anti-IL-10 mAbs |
Clone No. | AFD- 2H4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody binds mouse IL-10. Interleukin 10 is a major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. |
Alternative Name | IL10; Interleukin-10; Interleukin 10; Cytokine synthesis inhibitory factor (CSIF) |
UniProt | P18893 |
Immunogen | The original antibody was generated by immunizing New Zealand white rabbits with recombinant mouse IL-10 protein. |
Application Notes | The original rabbit IgG antibody binds mouse IL-10 with a high affinity and has a dissociation constant (Kd) of 1.38×10^(-10) M. A combination of 2H4 and 3F5 can be used in a double antibody sandwich ELISA, where 2H4 is used as a capture antibody and 3F5 is used as a detection antibody. The sensitivity of mouse IL-10 detection for this pair was reported to be 1.965pg/mL (CN116396384). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
