Anti-IL-4 mAbs

Cat. No.

MABL-2078

Name

Anti-IL-4 mAbs

Clone No.

AFD- AbAbS1-IL4

From

Recombinant Antibody

Isotype

Engineer antibody

Application

cytometric bead array, ELISA

Species Reactivity

Human

Basic Information

Specificity

This antibody binds human IL-4.   Interleukin-4 is a cytokine secreted primarily by mast cells, T- cells,   eosinophils, and basophils that plays a role in regulating antibody   production, hematopoiesis and inflammation, and the development of effector   T-cell responses. It induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It also induces expression of class II MHC molecules on   resting B-cells and enhances both secretion and cell surface expression of IgE and IgG1.

Alternative Name

IL4; BSF-1; Interleukin-4; B-cell   stimulatory factor 1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

UniProt

P05112

Immunogen

The original antibody was generated by immunizing   BALB/c mice with human interleukin-4.

Application Notes

This antibody can be used for detection of   IL-4 using ELISA. A combination of AbAbS1- IL4 and AbAbS2-IL4 was used for   the detection of IL-4 in a sandwich assay, where AbAbS1-IL4 was used as a   coating antibody and AbAbS2-IL4 was used as detection antibody. This   combination was also used in the generation of a cytometric bead array (CBA)   kit for detection of IL-4. The sensitivity of detection for this antibody   pair for the CBA kit was reported to be less than 0.5pg/mL (CN118388645).

Antibody First   Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.