Key features and details | |
Cat. No. | MABL-2090 |
Name | Anti-IL-6 mAbs |
Clone No. | AFD- 2G9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody binds mouse IL-6, a cytokine found in fibroblasts, monocytes/macrophages, T lymphocytes, B lymphocytes and a variety of tumor cells. IL-6 plays an important role in immune response, hematopoiesis, inflammation and stress response. |
Alternative Name | IL6; Interleukin-6; B-cell hybridoma growth factor; Interleukin HP-1 |
UniProt | P08505 |
Immunogen | The original antibody was generated by immunizing New Zealand white rabbits with recombinant Mouse IL-6 protein (Uniprot ID:P08505). |
Application Notes | This antibody binds mouse IL-6 with a binding affinity in the nanomolar range. This antibody was used as a labelling antibody in combination with 12E1 as a capture antibody for the development of a sandwich ELISA assay for detection of mouse IL-6. This antibody pair specifically recognized mouse IL-6 in samples with a sensitivity as low as 1.56pg/mL (CN116715763). |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |