Key features and details | |
Cat. No. | MABL-2120 |
Name | Anti-IL12RB1 mAbs |
Clone No. | AFD- 148F09 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | inhibition, SPR, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for human IL12RB1 |
Alternative Name | CD212; IL12Rb1#31; IL-12R-beta-1; Interleukin-12 receptor subunit beta- 1; L-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12RB1; IL-12 receptor beta component |
UniProt | P42701 |
Immunogen | |
Application Notes | The binding of the original version of this antibody (VHH) to IL12RB1 was characterized in an SPR (KD 0.23 nM) and ELISA (IC50 0.22 and 0.1 nM for IL-12 and IL-23, respectively). In its bi-specific constructs with Ab04387 (Anti-CD4 [3F11]), it served a functional role (US20220242958). |
Antibody First Published | |
Note on publication | The original publication describes the construction and characterization of various bi- specific antibodies. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
