Key features and details | |
Cat. No. | MABL-2126 |
Name | Anti-IL2R beta mAbs |
Clone No. | AFD- 5H4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody is specific for the murine interleukin-2 receptor beta chain. |
Alternative Name | CD122; IL-2Rβ; IL-2 receptor subunit beta; Interleukin-2 receptor subunit beta; High affinity IL-2 receptor subunit beta; p70-75 |
UniProt | P16297 |
Immunogen | This antibody was raised by immunising Lewis rats with transfected rat myeloma cell line YB2/0, expressing truncated murine IL-2R beta. |
Application Notes | This antibody has been used in flow cytometric analysis of IL-2R beta expression by thymocytes, lymph node cells and 3B4.15 T hybridoma cells (Ligons et al, 2012), as well as NK cells (He et al, 1996; Frenkel et al, 2016; Put et al, 2016; Elkabets et al, 2009). |
Antibody First Published | Malek et al. Biochemical Identity and Characterization of the Mouse Interleukin-2 Receptor β and γc Subunits. J Interferon Cytokine Res. 1995 May;15(5):447-54. PMID:7648447 |
Note on publication | Describes the original generation of this antibody, and its use in characterising the murine IL-2 receptor. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |