Key features and details | |
Cat. No. | MABL-2228 |
Name | Anti-lambda chain mAbs |
Clone No. | AFD- Mc24-1C6 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for the lambda chain of human IgG. The lambda chain is a constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. |
Alternative Name | Ig lambda chain C region MGC; Ig lambda-1 chain C region |
UniProt | P0CG04 |
Immunogen | The mouse version of this antibody was raised by immunizing a BALB/c mouse with purified human IgG. |
Application Notes | To characterize newly generated antibodies, flow cytometry was performed on tumor cells incubated with the new antibodies using the mouse version of this antibody to stain the antibodies (Suárez et al, 2004; pmid:15183930). |
Antibody First Published | Suárez et al. Human monoclonal antibodies produced in transgenic BABkappa,lambda mice recognising idiotypic immunoglobulins of human lymphoma cells Mol Immunol. 2004 Jul;41(5):519-26. PMID:15183930 |
Note on publication | Human monoclonal anti-human Id-IgM antibodies were generated in mice and characterized for therapy of patients with a B cell malignancies. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
