Key features and details | |
Cat. No. | MABL-2231 |
Name | Anti-lambda light chain mAbs |
Clone No. | AFD- 8-H9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, FC |
Species Reactivity | Ferret (Mustela putorius furo) |
Basic Information | |
Specificity | This antibody is specific for the lambda light chain of ferret B cell immunoglobulin. |
Alternative Name | B cell IgL; Ig; ferret immunoglobulin; lambda light chain; H9 |
UniProt | |
Immunogen | The original mouse IgG1 version of this antibody was raised against ferret immunoglobulins (IgG + IgM). |
Application Notes | This antibody is specific for the ferret lambda light chain of B cell surface receptor (BCR) and enables segreation of kappa and lambda B cells representing great improvement over polyclonal anti-ferret Ig. It can be used as an indicator of B cell malignancies such as multiple myeloma. It was screened for reactivity against ferret peripheral blood mononuclear cells by FCM what demonstrated specificity for CD79B+ B cells (Kirchenbaum and Ross, 2017; pmid:28286781). |
Antibody First Published | Kirchenbaum and Ross Generation of Monoclonal Antibodies against Immunoglobulin Proteins of the Domestic Ferret (Mustela putorius furo) J Immunol Res. 2017;2017:5874572. PMID:28286781 |
Note on publication | Describes the generation of eight unique murine monoclonal antibodies (mAbs) with specificity for ferret immunoglobulin (Ig). |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
