Key features and details | |
Cat. No. | MABL-2239 |
Name | Anti-Langerin mAbs |
Clone No. | AFD- 4C7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC, IHC-Fr |
Species Reactivity | Pig, Human, Cynomolgus Monkey, Mouse |
Basic Information | |
Specificity | This antibody binds to the ectodomain of Langerin (CD207). |
Alternative Name | CD207; C-type lectin domain family 4 member K; CLC4K |
UniProt | Q9UJ71 |
Immunogen | Langerin ectodomain fused to human IgFc |
Application Notes | This antibody can be used to identify Langerin-positive dendritic cells. This antibody has also been used to specifically target vaccine-peptides to dendritic cells. |
Antibody First Published | Flamar et al. Noncovalent assembly of anti-dendritic cell antibodies and antigens for evoking immune responses in vitro and in vivo. J Immunol. 2012 Sep 1;189(5):2645-55. PMID:22865916 |
Note on publication | Describes the use of 4C7 in targeting vaccine antigens to dendritic cells. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
