Key features and details | |
Cat. No. | MABL-2253 |
Name | Anti-LGI1 mAbs |
Clone No. | AFD- N283/7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, ICC, ELISA, IF, IHC |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for mouse LGI1 and cross-reacts with rat and human LGI1. It does not cross-react with LGI2, LGI3, or LGI4. |
Alternative Name | Leucine-Rich Glioma-Inactivated 1; Leucine rich glioma inactivated 1; Epitempin-1; EPITEMPIN; EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; UNQ775/PRO1569 |
UniProt | Q9JIA1 |
Immunogen | The original antibody was generated by immunizing Balb/c mice with fusion protein amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse LGI1. |
Application Notes | This antibody can be used for IB, ICC, and IHC (RRID: AB_2877432). Independently, it was used in an IF assay (Hivert et al., 2019; PMID: 30598502), an ELISA (Kornau et al., 2020; PMID: 31900946), and an IHC assay (Kozar, 2022; DOI: 10.7488/era/2379). |
Antibody First Published | Hivert et al. ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment. J Cell Sci. 2019 Jan 16;132(2):jcs219774. doi: 10.1242/jcs.219774. PMID:30598502 |
Note on publication | The original publication investigates the role of ADAM22 and ADAM23 in modulating the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
