Anti-Lycopene mAbs

Cat. No.

MABL-2289

Name

Anti-Lycopene mAbs

Clone No.

AFD- 6B9

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA, IF

Species Reactivity

Species independent

Basic Information

Specificity

This antibody is highly specific for   lycopene and does not recognize other carotenoids such as lutein. Lycopene is   a naturally occurring red pigment, which belongs to the family of   carotenoids. It is found in tomatoes, watermelon and papaya. Lycopene is one   of the most powerful antioxidants, belonging to the tetraterpene group, whose   anti-radical activity exceeds the antioxidant potential of tocopherol, beta-   carotene and ascorbic acid. The highly unsaturated chemical structure of lycopene predetermines its ability to react with many substances containing   or generating singlet molecular oxygen such as peroxyl radicals, hydrogen   peroxide and hypochlorite.

Alternative Name

Carotene; carotenoid; C40H56; CAS: 502-65-8;   CHEBI:15948

UniProt

Immunogen

The original antibody was generated by   immunizing BALB/c mice with lycopene-gold conjugated colloidal particles.

Application Notes

The binding reactivity of the original   antibody towards lycopene was determined using ELISA. This antibody was also   able to recognize lycopene inclusions in the settings of indirect immunofluorescence experiments. This antibody can also be used for the   visualization of lycopene distribution within cultured human hepatocytes and   alveolar macrophages which were pre-incubated with this carotenoid for 48   hours (WO2018115885).

Antibody First   Published

Petyaev et al. Antibodies against   carotenoids (WO2018115885).

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.