Key features and details | |
Cat. No. | MABL-2303 |
Name | Anti-M-CSF mAbs |
Clone No. | AFD-100 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | inhibition, SPR |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for M-CSF. |
Alternative Name | CSF-1; MCSF; PG-M-CSF; Lanimostim; Macrophage colony-stimulating factor; Macrophage colony-stimulating factor 1; Proteoglycan macrophage colony-stimulating factor |
UniProt | P09603 |
Immunogen | The original format of the antibody was generated by immunizing transgenic mice with human M-CSF. |
Application Notes | The original format of the antibody inhibited mouse monocytic cell proliferation in response to M-CSF. Further, the IC50 for inhibition of mouse nonocytic cell proliferation was determined for the antibody (IC50 = 15.3 nM). The binding properties of the original format of the antibody were analyzed using SPR analysis (Kd= 0.2 pM) (US7326414B2). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
