Key features and details | |
Cat. No. | MABL-2345 |
Name | Anti-MerTK mAbs |
Clone No. | AFD- Ab2000 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | inhibition, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody specifically binds to human MerTK. |
Alternative Name | Tyrosine-protein kinase Mer; EC:2.7.10.1; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK |
UniProt | Q12866 |
Immunogen | The original antibody was generated by phage display method. A phage display library was screened against the extracellular domain of human and/or mouse MerTK. |
Application Notes | The specificity of the IgG1 format of the antibody was confirmed by ELISA analysis. The antibody bound to cellularly expressed full length human MerTK in a dose responsive manner, with EC50 values in the picomolar to nanomolar range, as determined by FACS. The antibody inhibited Gas6 binding to hMerTK in a dose responsive manner, with an IC50 of 1 nM (WO2019084307A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
