Anti-MHC Class I mAbs

Cat. No.

MABL-2364

Name

Anti-MHC Class I mAbs

Clone No.

AFD- OX-27

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, FC

Species Reactivity

Rat

Basic Information

Specificity

This antibody recognizes a polymorphic   determinant (c haplotype) of rat Class I MHC Antigen (RT-1A).

Alternative Name

Major Histocompatibility Complex 1; MRC   OX27; OX27

UniProt

Immunogen

This antibody was prepared by immunizing   BALB/c mice with rat phytohemagglutinin blasts.

Application Notes

This antibody binds to rat MHC Class I, and   has been used to show that, in an in vivo rat model, antibodies against MHC  class I antigens from stored blood may precipitate transfusion-related acute   lung injury (Kelher, 2009).

Antibody First   Published

Jeffries et al. Authentic T helper CD4 (W3/25)   antigen on rat peritoneal macrophages. J Exp Med. 1985 Jul 1;162(1):117-27.   PMID:3159821

Note on publication

Describes the original use of this antibody   in immunoprecipitations to generate an MHC I precipitate for use in   comparative SDS page analysis.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.