Key features and details | |
Cat. No. | MABL-2364 |
Name | Anti-MHC Class I mAbs |
Clone No. | AFD- OX-27 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC |
Species Reactivity | Rat |
Basic Information | |
Specificity | This antibody recognizes a polymorphic determinant (c haplotype) of rat Class I MHC Antigen (RT-1A). |
Alternative Name | Major Histocompatibility Complex 1; MRC OX27; OX27 |
UniProt | |
Immunogen | This antibody was prepared by immunizing BALB/c mice with rat phytohemagglutinin blasts. |
Application Notes | This antibody binds to rat MHC Class I, and has been used to show that, in an in vivo rat model, antibodies against MHC class I antigens from stored blood may precipitate transfusion-related acute lung injury (Kelher, 2009). |
Antibody First Published | Jeffries et al. Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages. J Exp Med. 1985 Jul 1;162(1):117-27. PMID:3159821 |
Note on publication | Describes the original use of this antibody in immunoprecipitations to generate an MHC I precipitate for use in comparative SDS page analysis. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
