Key features and details | |
Cat. No. | MABL-2445 |
Name | Anti-Myotoxin II mAbs |
Clone No. | AFD- TPL0039_05_E2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | plate test |
Species Reactivity | Bothrops asper (Terciopelo) |
Basic Information | |
Specificity | TPL0039_05_E2 antibody recognizes myotoxin-II, which is one of the major toxins in the venom of the snake Bothrops asper (Terciopelo). |
Alternative Name | Basic phospholipase A2 homolog 2; svPLA2 homolog; Myotoxin-II; MtxII |
UniProt | P24605 |
Immunogen | In order to raise the antibody, three phage display selection rounds were performed against myotoxin-II, using the IONTAS library. The IONTAS library is a human antibody phage display library of 4 x 10^10 clones displaying antibodies in the short chain variable fragment (scFv) form. |
Application Notes | TPL0039_05_E2 scFv (and its other antibody formats) is recommended for the research on anti-myotoxin-II (Bothrops asper (Terciopelo)) treatment (for snakebites). |
Antibody First Published | Sørensen et al. Discovery of human recombinant antibodies against myotoxin-II from the notorious Bothrops asper. 10.13140/RG.2.2.35413.47847. |
Note on publication | This poster describes the generation and characterization of the TPL0039_05_E2 antibody, as a potential treatment for Bothrops asper snakebites. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
