Key features and details | |
Cat. No. | MABL-2530 |
Name | Anti-Nucleoprotein mAbs |
Clone No. | AFD- MARV-A |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | in vitro, WB, ELISA |
Species Reactivity | Lake Victoria marburgvirus |
Basic Information | |
Specificity | This antibody is specific for the Marburgvirus Nucleoprotein. |
Alternative Name | NP; Protein N; Nucleoprotein; Nucleocapsid protein |
UniProt | P27588 |
Immunogen | The original antibody was raised by immunizing a llama with the Marburgvirus Nucleoprotein. |
Application Notes | The original version of this antibody was used for an ELISA on nucleoprotein from polio (Garza et al., 2017; PMID:29038656, Darling et al., 2017; PMID:29021793). The monomeric and dimeric version of this antibody were used for a western blot on HEK 293T cells (Garza et al., 2017; PMID:29038656). Furthermore the ability of this antibody to crosslink nucleoprotein (NP) in vitro was tested (Darling et al., 2017; PMID:29021793). |
Antibody First Published | Darling et al. Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging Front Immunol. 2017; 8: 1197. PMID:29021793 |
Note on publication | The original paper studied whether RNC would be ideal targets for crosslinkers engineered to promote aberrant protein–protein interactions. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
