Anti-Oct3/4 mAbs

Cat. No.

MABL-2537

Name

Anti-Oct3/4 mAbs

Clone No.

AFD- 41B1

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, IHC

Species Reactivity

Human

Basic Information

Specificity

The original antibody is specific for   OCT3/4. OCT3/4 is a transcription factor that binds to the octamer motif   (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 or SOX15 on DNA and   controls the expression of a number of genes involved in embryonic   development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early   embryogenesis and for embryonic stem cell pluripotency.

Alternative Name

C-10; KS20.8; POU5F1; Oct4; POU domain,   class 5, transcription factor 1; POU domain, class 5, transcription factor 1;   Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4;   Octamer-binding transcription factor 3; OTF-3; CGMCC NO 20779

UniProt

Q01860

Immunogen

The original antibody was generated by   immunizing mice with recombinant protein OCT3/4.

Application Notes

The antibody 41B1 and the commercial antibody   C-10 were used to stain collagen tumor, dysgerminoma and testicular tissue in immunohistochemistry. Results showed the antibody specificity is comparable   to the commercial antibody. Further, the staining intensity of the antibody   41B1 was higher than the commercial antibody (CN113072642A).

Antibody First   Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.