Key features and details | |
Cat. No. | MABL-2539 |
Name | Anti-Oestrone-3-glucuronide mAbs |
Clone No. | AFD-3910 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody binds to E3G with an affinity of 1.43 nM. |
Alternative Name | E3G |
UniProt | |
Immunogen | Human E3G. |
Application Notes | The antibody is specific for Oestrone-3-glucuronide (E3G), a urinary metabolite of 17β- estradiol, a hormone secreted by the developing ovarian follicles. The monoclonal antibodies can be used clinically to detect levels of E3G in urine samples of women, providing a non-invasive test for determining the fertile period, indicating the time of ovulation. |
Antibody First Published | He M, Gani M, Livnah O, Stura EA, Beale D, Coley J, Wilson IA, Taussig MJ. Sequence, specificity and crystallization of an oestrone-3-glucuronide antibody (3910). Immunology. 1997 Apr;90(4):632-9. PMID:9176119 |
Note on publication | Describes the generation of the monoclonal antibody 3910, specific for oestrone-3- glucuronide (E3G). The antibody has neutralising activity, and its crystal structure allows us to determine the binding interactions between 3910 and its ligand, |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
