Anti-Outer membrane protein mAbs [CB-NM.2](MABL-2559)

Cat. No.

MABL-2559

Name

Anti-Outer membrane protein mAbs

Clone No.

AFD- CB-NM.2

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, ELISA

Species Reactivity

Neisseria meningitidis

Basic Information

Specificity

This antibody is specific for a five amino   acid region (S/T)VETG located in the main variable region (VR) VR1 which was   present in all N. meningitidis strains. It recognizes class 3 outer membrane   protein of Neisseria meningitidis. This antibody can recognize fifty six   strains belonging to seven serogroups: A, B, 29E, L, X, Y, Z, and five   serotypes: 1, 4, 5, 12, 13 but did not recognize the serotypes 2, 6, 9, 11,   14, 15, 18 and 19.

Alternative Name

class 3 outer membrane protein; 15F9; NM-2

UniProt

Immunogen

The original antibody was generated by immunizing mice with serotype antigen preparations from case isolate B385 strain of Neisseria meningitidis, from Havana.

Application Notes

The binding reactivity of this antibody   against fifty six strains of Neisseria meningitidis belonging to seven   serogroups: A, B, 29E, L, X, Y, Z, and five serotypes: 1, 4, 5, 12, 13 was   assessed using whole cell ELISA. This antibody can also be used in the   detection of these serogroups and serotypes using western blot (Guillen et   al., 1997).

Antibody First   Published

Guillen et al. Molecular analysis Neisseria   meningitidis class 3 outer membrane protein in strains recognized by the   monoclonal antibody CB-Nm.2. Biotechnologia Applicada 1997; Vol -14:23-30.

Note on publication

This paper analyzes the reactivity of this   antibody with various serogroups and serotypes of N. meningitidis and   determines the binding epitope of this antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.