Anti-P-glycoprotein mAbs

Cat. No.

MABL-2569

Name

Anti-P-glycoprotein mAbs

Clone No.

AFD- MRK16

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, FC, IF

Species Reactivity

Human

Basic Information

Specificity

Recognizes a discontinuous extracellular epitope on P-glycoprotein.

Alternative Name

ABCB1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; CD243; MDR1; PGP; PGY1

UniProt

P08183

Immunogen

Drug resistant K-562 cells.

Application Notes

Antibody First   Published

Hamada H, Tsuruo T. Functional role for the   170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as   revealed by monoclonal antibodies. Proc Natl Acad Sci U S A. 1986   Oct;83(20):7785-9. PMID:2429319

Note on publication

Describes the generation of the antibody and   its ability to modulate drug cytotoxicity in vitro.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.