Key features and details | |
Cat. No. | MABL-2569 |
Name | Anti-P-glycoprotein mAbs |
Clone No. | AFD- MRK16 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | Recognizes a discontinuous extracellular epitope on P-glycoprotein. |
Alternative Name | ABCB1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; CD243; MDR1; PGP; PGY1 |
UniProt | P08183 |
Immunogen | Drug resistant K-562 cells. |
Application Notes | |
Antibody First Published | Hamada H, Tsuruo T. Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc Natl Acad Sci U S A. 1986 Oct;83(20):7785-9. PMID:2429319 |
Note on publication | Describes the generation of the antibody and its ability to modulate drug cytotoxicity in vitro. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
