Key features and details | |
Cat. No. | MABL-2604 |
Name | Anti-PAR2 mAbs |
Clone No. | AFD- 1B5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human PAR2 or proteinase-activated receptor 2 upstream to its cleavage site. PAR2 acts as a receptor for trypsin and trypsin-like enzymes coupled to G proteins. |
Alternative Name | F2RL1; PAR-2; GPR11; Proteinase-activated receptor 2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1 |
UniProt | P55085 |
Immunogen | The original antibody was generated by immunizing XenoMouse™ with PAR-2 antigen. |
Application Notes | The initial screening of this antibody for reactivity for PAR2 was done using ELISA. The equilibrium dissociation constant (KD) of this antibody was obtained using KinExA® software and by “n- curve analysis” and it was reported that the original antibody had a KD of 3.39 nM with a 95% confidence interval of 1.36 to 5.47 nM (US8357367). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
