Key features and details | |
Cat. No. | MABL-2964 |
Name | Anti-SpA-E mAbs |
Clone No. | AFD-10901 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Staphylococcus aureus |
Basic Information | |
Specificity | This antibody is specific for SpA-E of S.aureus. S.aureus is a bacteria that causes MRSA in humans, but can also cause a wide range of other infections. |
Alternative Name | immunoglobulin binding protein of Staphylococcus aureus; IGBP of Staphylococcus aureus; Immunoglobulin G-binding protein A; IgG-binding protein A; Staphylococcal protein A |
UniProt | A0A0H3K686 |
Immunogen | The original antibody was generated by panning a human library against SpA. |
Application Notes | The affinity of the antibody to bind SpA-E was determined by a standard optical interferometry method (KD 5nM). The binding of the antibody to SpA on live S. aureus TCH1516 (USA300 MRSA strain) was tested by flow cytometry. The antibody showed inhibition of IgG binding to SpA on S. aureus cells in a flow cytometry-based surface staining assay. The antibody showed a significant reduction in S. aureus survival by opsonophagocytic killing (OPK) activity measurement (CN108064241A). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
