Key features and details | |
Cat. No. | MABL-2998 |
Name | Anti-SV40 large Tumor ntigen mAbs |
Clone No. | AFD-405 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA |
Species Reactivity | SV40 |
Basic Information | |
Specificity | The antibody binds specifically to the carboxy-terminus of the SV40 T antigen. |
Alternative Name | SV40TA; Simian Virus 40 large T antigen |
UniProt | P03070 |
Immunogen | SV40 T antigen from Sf9 insect cells. |
Application Notes | The antibody binds to the SV40 T antigen, a hexameric protein that acts as a proto- oncogene capable of transforming cells, for examble via inhibition of pRB or p53. |
Antibody First Published | Shearer et al. Molecular characterization of immunoglobulin variable regions from murine monoclonal antibodies specific for simian virus 40 large tumour antigen. Scandinavian Journal of Immunology 1994; 40(4)415-422 PMID:7939414 |
Note on publication | Describes the generation of three monoclonal antibodies against the SC40 T-antigen. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |