Key features and details | |
Cat. No. | MABL-3051 |
Name | Anti-TGF beta1 mAbs |
Clone No. | AFD- SL15S |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | neutralizing, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for TGFβ1. It does not cross-react with TGFβ2 or TGFβ3. |
Alternative Name | TGFβ1; CAT-191; Kylie scFv; TGFB1, TGFB, Transforming growth factor beta-1, TGF-beta-1; Transforming growth factor beta-1 proprotein |
UniProt | P01137 |
Immunogen | The original antibody was generated by panning a human phage antibody library against TGF beta1. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis. The ability of the scFv fragment to recognise TGFβ1 and neutralise binding of TGFβ1 to A549 cells was measured in the radioreceptor assay. The scFv fragment was a highly potent, neutralising antibody for TGFβ1, with IC50 values in the range 0.03 to 0 1 nM. In particular, the scFv fragment could neutralise active, but not latent, TGFβ1 (US7151169B2). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
