Key features and details | |
Cat. No. | MABL-3136 |
Name | Anti-Triclocarban mAbs |
Clone No. | AFD-T9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Species independent |
Basic Information | |
Specificity | This antibody binds Triclocarban (TCC), which is an antibacterial chemical. This antibody also shows some cross reactivity with structurally similar compounds like 2′-OH TCC and 4,4′-Dichlorocarbanilide. |
Alternative Name | TCC; 1-(4-chlorophenyl)-3-(3;4-dichlorophenyl)urea; bactericide |
UniProt | |
Immunogen | The original antibody was generated by immunizing Llama glama intramuscularly with 600 μg of the TCC-Thy conjugate in Freund Incomplete Adjuvant. |
Application Notes | The binding of this antibody to triclocarban was confirmed using ELISA. SPR was used to measure the binding affinity of this antibody and it was reported to be Kd= 1.1 nM. |
Antibody First Published | Rosa et al. Competitive Selection from Single Domain Antibody Libraries Allows Isolation of High-Affinity Antihapten Antibodies That Are Not Favored in the llama Immune Response. Anal Chem. 2011 Sep 15; 83(18): 7213–7220. PMID:21827167 |
Note on publication | Describes the isolation of high affinity nanobodies against Triclocarban. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
