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Anti-α-GalCer:mCD1d1 complexes coupled to Mycobacterium tuberculosis PPD mAbs

简要描述:

L363 binds specifically to the α-GalCer:mCD1d complex at an epitope formed by α-GalCer bound to mCD1d.

产品参数:

Cat. No.:MABL-3324

Species:Engineer

Species Reactivity:Mouse

Type:Recombinate

Application:IF;Block, FC

详细介绍

Key features and   details


Cat. No.

MABL-3324

Name

Anti-α-GalCer:mCD1d1 complexes coupled to Mycobacterium tuberculosis PPD mAbs

Clone No.

AFD- L363

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IF;Block, FC

Species Reactivity

Mouse

Basic Information


Specificity

L363 binds specifically to the   α-GalCer:mCD1d complex at an epitope formed by α-GalCer bound to mCD1d.

Alternative Name


UniProt


Immunogen

The immunogen used to generate L363 was   C-terminally BirA-His-tagged soluble mCD1d/mβ2m/KRN7000 complex cross-linked   with purified protein derivative (PPD) from M. tuberculosis strain H37Ra.

Application Notes


Antibody First   Published

Yu et al. Structural basis for the  recognition of C20:2-αGalCer by the invariant natural killer T cell   receptor-like antibody L363. J Biol Chem. 2012 Jan 6;287(2):1269-78   PMID:22110136

Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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