Key features and details | |
Cat. No. | MABL-330 |
Name | Anti-8-OH-Adenosine mAbs |
Clone No. | AFD- 8A9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA |
Species Reactivity | Species independent |
Basic Information | |
Specificity | This antibody is specific for 8-OH-adenosine. |
Alternative Name | adenosine; hydroxyadenosine; hydroxy-adenosine; 8-hydroxyadenosine; 8 hydroxy adenosine; Ade; 8-Ox-Ade |
UniProt | |
Immunogen | This antibody was raised by immunizing balb/c mice subcutaneously with 8-OH-adenosine conjugated to keyhole limpet hemocyanin. |
Application Notes | 8A9 is recommended for the detection of 8-OH-Adenosine. In an inhibition experiment it was tested wether a ligand for 8-OH-adenosine could inhibit the binding of this antibody to its antigen. It was shown that a concentration betweeen 1 and 5 um ihibits the antibody binding to its antigen (US6900291B2). The ability this antibody to detect 8-OH-Ade lesions in physiological DNA was tested. A dot blot was used to test this (US6900291B2). This antibody was tested for binding to 8-OH-adenosine conjugated BSA in an ELISA on 96-well Probind plates (US6900291B2). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
