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Anti-acetylcholinesterase mAbs

简要描述:

The antibody is specific for acetylcholinesterase.

产品参数:

Cat. No.:MABL-348

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:BLI, ELISA

详细介绍

Key features and details

Cat. No.

MABL-348

Name

Anti-acetylcholinesterase mAbs

Clone No.

AFD- 1G

From

Recombinant Antibody

Isotype

Engineer antibody

Application

BLI, ELISA

Species Reactivity

Human

Basic Information

Specificity

The antibody is specific for acetylcholinesterase.

Alternative Name

EC:3.1.1.7; AChE

UniProt

P22303

Immunogen

The original antibody was generated   immunizing mice with full-length recombinant human acetylcholinesterase   (rHuAChE).

Application Notes

The specificity of the antibody was confirmed by ELISA analysis (Kd = 1 nM). The binding affinity of the antibody  to AChE was measured by BLI (Kd= 0.32 nM) (Dafferner et al., 2017; PMID:   28892361).

Antibody First Published

Dafferner et al. Immunopurification of  Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure Chem Res Toxicol. 2017 Oct 16; 30(10): 1897–1910. PMID:28892361

Note on publication

The original paper describes the generation and characterization of the original antibody.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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