Anti-AdiC mAbs

Cat. No.

MABL-359

Name

Anti-AdiC mAbs

Clone No.

AFD- Fab21

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA

Species Reactivity

E. coli, Salmonella enterica

Basic Information

Specificity

Binds to the AdiC transporter of various enteric bacteria, including E.coli and S. enterica.

Alternative Name

Arginine: Agmantine Antiporter

UniProt

P60061

Immunogen

E.coli AdiC.

Application Notes

This antibody binds to AdiC of enteric bacteria. AdiC is a membrane protein acting as a transporter that imports arginine from the gastric juice and exports its decarboxylation product   agmatine along with protons. AdiC is responsible for the acid-resistance of enteric bacteria. The antibody does not inhibit function of the transporter.

Antibody First Published

 Fang et al. Structure of a prokaryotic   virtual proton pump at 3.2 A resolution. Nature 2009; 460(7258):1040-1043   PMID:19578361

Note on publication

Describes the crystallisation of AdiC, an L-arginine transporter, with the aid of an AdiC-binding Fab.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.