Key features and details | |
Cat. No. | MABL-384 |
Name | Anti-alpha-gal epitope mAbs |
Clone No. | AFD- m86 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, FC |
Species Reactivity | Species independent |
Basic Information | |
Specificity | This antibody binds to the alpha-gal epitope on glycoproteins and glycolipids. |
Alternative Name | A-Gal; Gal-alpha-1 – 3Gal-beta-1 – 4GlcNAc-R |
UniProt | |
Immunogen | Rabbit red cells, on which α-gal is the major carbohydrate epitope, were injected into alpha 1,3 galactosyltransferase knock-out mice. |
Application Notes | This antibody binds to the alpha-gal epitope found on many glycoproteins and glycolipids of non-primate mammalis, prosimians and New World monkeys. Antibodies agains the alpha-gal epitopes occur naturally in Old World monkeys, apes and humans, and induce xenograft rejection from nonprimate animals. |
Antibody First Published | Chen, Radic and Galili Genes coding evolutionary novel anti-carbohydrate antibodies studies on anti-Gal production in alpha 1,3 galactosyltransferase knock out mice. Mol Immunol.2000 Jun;37(8): 455-66. PMID：11090880 |
Note on publication | Describes the generation and characterization of anti-gal epitope antibodies raised in alpha 1,3 galactosyltransferase knock-out mice. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
