Key features and details | |
Cat. No. | MABL-612 |
Name | Anti-Capsular polysaccharide mAbs |
Clone No. | AFD- 4-2-C (7H9-4) |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Neisseria meningitidis serogroup c |
Basic Information | |
Specificity | This antibody is specific for capsular polysaccharides of Neisseria meningitidis serogroup C, showing no reaction against encapsulated serogroup B organisms. |
Alternative Name | Neisseria meningitidis serogroup C capsular polysaccharide; NmC |
UniProt | |
Immunogen | The original antibody was generated by immunizing mice with whole encapsulated N. meningitidis. |
Application Notes | This antibody can be used for the identification of capsular polysaccharide of Neisseria meningitidis serogroup C using an ELISA. The cross reactivity of this antibody towards various serogroups of N. meningitidis was checked using ELISA (PMID: 15589322). This antibody can also be used in a whole cell ELISA at a 1: 2000 dilution for detection of serogroup C (PMID: 12721942) |
Antibody First Published | Berry et al. Molecular analysis of monoclonal antibodies to group variant capsular polysaccharide of Neisseria meningitidis: recurrent heavy chains and alternative light chain partners. Mol Immunol. 2005 Feb; 42(3): 335–344. PMID:15589322 |
Note on publication | Describes the generation of antibodies against serogroup B and C of Neisseria meningitidis. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |