Key features and details | |
Cat. No. | MABL-3498 |
Name | Anti-HA mAbs |
Clone No. | FB75 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | NTRL, ELISA |
Species Reactivity | Influenza A Virus (several subtypes) |
Basic Information | |
Specificity | This antibody specifically recognizes the conformational epitope in the stem region of HA in which amino acid sequences are highly conserved in H1N1, H5N1, H6N1, and H9N2 subtypes of Influenza A Virus. This antibody uses the VH3-23*01, D3-3*01, JH4*02, VL2-23*02 and JL1*01. This antibody does not cross react with HA in H2N2, H3N2 and H7N7 subtype of Influenza A virus. This antibody has no effect on haemagglutination-inhibition activity. |
Alternative Name | hemagglutinin; haemagglutinin |
UniProt | |
Immunogen | Made by immortalizing IgG-expressing B cells from individuals following vaccination with seasonal influenza vaccine, containing H1 and H3 influenza Virus subtypes. |
Application Notes | |
Antibody First Published | Corti, D. et al Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine. J Clin Invest 120, 1663–1673 (2010).PMID:20389023 |
Note on publication | Describes the isolation and analysis of a panel of human antibodies from vaccinated individuals - especially performance in Virus neutralization assays. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
