Anti-HA mAbs [FE17](MABL-3500)

Cat. No.

MABL-3500

Name

Anti-HA mAbs

Clone No.

FE17

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA

Species Reactivity

InfluenzaAVirus (severalsubtypes)

Basic Information

Specificity

This antibody specifically recognizes the conformational epitope in the Ca2 region of HA (as assessed by the isolation   of viral escape mutants all carrying a single S to N point mutation at   position 145, according to H3 numbering) in which amino acid sequences are   conserved in H1N1 and H5N1 subtypes of Influenza A Virus. This antibody uses   the VH4-39*01, D3-9*01, JH4*02, VL1-44*01 and JL3*02 This antibody does not   cross react with HA in H2N2, H3N3, H6N1, H7N3 and H9N2 subtypes of Influenza   A virus. This antibody has haemagglutination-inhibition activity.

Alternative Name

hemagglutinin; haemagglutinin

UniProt

Immunogen

Made by immortalizing IgG-expressing B cells   from individuals following vaccination with seasonal influenza vaccine,   containing H1 and H3 influenza Virus subtypes.

Application Notes

Antibody First   Published

Corti, D. et al   Heterosubtypic neutralizing antibodies are produced by individuals immunized   with a seasonal influenza vaccine. J Clin Invest 120, 1663–1673   (2010).PMID:20389023

Note on publication

Describes the isolation   and analysis of a panel of human antibodies from vaccinated individuals and   its evaluation using Virus neutralization assays.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.