Name
HIV-1 GAG
Cat. No.
MAG-4546
Tag/Conjugates
His
Source
Escherichia Coli.
Shipped
At Room Temperature
Description
HIV-1 GAG
Introduction
Human immunodeficiency virus (HIV) is a retrovirus which may lead to a immune systembegins failure and to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. The Gag protein is the major structural protein required for virus assembly. It is synthesizedas a polyprotein in the cytosol of an infected cell and contains 4 functional segments. Gag alone is sufficient to produce buddingvirus-like particles (VLP's) due to multimerization of roughly 2000 Gag molecules per virion.The Gag proteins take part throughout the viral life-cycle, including the assembly and release of viral particles, theirsubsequent maturation into infectious virions, and during the events occurring between therelease of capsids into newly infected cells and the integration of proviral DNA.
Physical Appearance
His
Formulation
Escherichia Coli.
Stability
At Room Temperature
Purity
Greater than 78.0% as determined by SDS-PAGE.
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Applications
Western Blotting, SDS Page
Immunological functions
/
Purification Method
/
Specificity
/
