Key features and details | |
Cat. No. | MABL-3348 |
Name | Anti-Der p 7 mAbs |
Clone No. | AFD-WH9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Block, ELISA |
Species Reactivity | House Dust Mite |
Basic Information | |
Specificity | This antibody binds to the house dust mite allergen Der p 7 and competes with a subset of naturally occurring IgE. |
Alternative Name | Mite allergen Der p 7; Allergen Der p VII; Major mite fecal allergen Der p 1; Dermatophagoides farinae allergen 1; Dermatophagoides pteronyssinus allergen 1 |
UniProt | P49273 |
Immunogen | Recombinant Der p 7. |
Application Notes | The antibody binds specifically to Der p 7, a house dust mite allergen which plays an important role in inflammatory and hypersensitive reactions. The antibody WH9 binds to an epitope which is overlapping with that of IgE, thereby inhibiting its binding by up to 60%. By preventing mast cell degranulation, the antibody can be useful in the development of hypoallergenic vaccines. |
Antibody First Published | Shen et al. Characterization of the house dust mite allergen Der p 7 by monoclonal antibodies. Clin Exp Allergy. 1995 May;25(5):416-22. PMID:7553244 |
Note on publication | Describes the generation and characterization of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
