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Recombinant ALDH6A1 Human Protein [E.coli.] (MAG-3020)

简要描述:

Recombinant ALDH6A1 Human Protein from E.coli.expression and purification

产品参数:

Name:ALDH6A1 Human

Cat. No.:MAG-3020

Tag/Conjugates:His

Source:Escherichia Coli.

Shipped:Shipped with Ice Packs

产品价格:¥0

详细介绍
Name
ALDH6A1 Human
Cat. No.
MAG-3020
Tag/Conjugates
His
Source
Escherichia Coli.
Shipped
Shipped with Ice Packs
Description
ALDH6A1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 525 amino acids (34-535 a.a) and having a molecular mass of 56.8kDa.
Introduction
ALDH6A1 or Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial is a mitochondrial methylmalonate semialdehyde dehydrogenase. ALDH6A1 participates in the valine and pyrimidine catabolic pathways. ALDH6A1 catalyzes the irreversible oxidative decarboxylation of malonate, propionyl-CoA and methylmalonate semialdehydes to acetyl. ALDH6A1 deficiency is distinguished by high levels of beta-alanine, 3-hydroxypropionic acid, and the two isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Purification Method
/
Physical Appearance
Sterile Filtered colorless solution.
Formulation
ALDH6A1 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Biological Activity
/
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Synonyms
MMSADHA, MMSDH , Aldehyde Dehydrogenase 6 Family, Member A1, Methylmalonate-Semialdehyde Dehydrogenase [Acylating], Mitochondrial, Mitochondrial Acylating Methylmalonate-Semialdehyde Dehydrogenase, Malonate-Semialdehyde Dehydrogenase [Acylating], Aldehyde Dehydrogenase Family 6 Member A1, Malonate-Semialdehyde Dehydrogenase, EC 1.2.1.18, EC 1.2.1.27.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGS SSSVPTV KLFIGGKFVE SKSDKWIDIH NPATNEVIGR VPQATKAEMD AAIASCKRAF PAWADTSVLS RQQVLLRYQQ LIKENLKEIA KLITLEQGKT LADAEGDVFR GLQVVEHACS VTSLMMGETM PSITKDMDLY SYRLPLGVCA GIAPFNFPAM IPLWMFPMAM VCGNTFLMKP SERVPGATML LAKLLQDSGA PDGTLNIIHG QHEAVNFICD HPDIKAISFV GSNKAGEYIF ERGSRHGKRV QANMGAKNHG VVMPDANKEN TLNQLVGAAF GAAGQRCMAL STAVLVGEAK KWLPELVEHA KNLRVNAGDQ PGADLGPLIT PQAKERVCNL IDSGTKEGAS ILLDGRKIKV KGYENGNFVG PTIISNVKPN MTCYKEEIFG PVLVVLETET LDEAIQIVNN NPYGNGTAIF TTNGATARKY AHLVDVGQVG VNVPIPVPLP MFSFTGSRSS FRGDTNFYGK QGIQFYTQLK TITSQWKEED ATLSSPAVVM PTMGR.
Background
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