Name
KLK8 Mouse
Cat. No.
MAG-3320
Tag/Conjugates
His
Source
Sf9, Baculovirus cells.
Shipped
Shipped with Ice Packs
Description
KLK8 Mouse Recombinant produced in Sf9 is a single, glycosylated polypeptide chain containing 240 amino acids (29-260) and having a molecular mass of 26.5kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). The KLK8 is fused to an 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
Introduction
Kallikrein-8
is a serine protease which degrades various proteins such as casein,
fibrinogen, kininogen, fibronectin and collagen type IV. Kallikrein-8 takes
part in the formation and maturation of orphan and small synaptic boutons in
the Schaffer-collateral pathway, regulates Schaffer-collateral long-term
potentiation in the hippocampus and is essential for memory acquisition and
synaptic plasticity. Kallikrein-8 participates in the secondary phase of
pathogenesis following spinal cord injury and also takes part in skin
desquamation and keratinocyte proliferation.
Purification Method
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Physical Appearance
Sterile Filtered colorless solution.
Formulation
KLK8 protein 0.5mg/ml is supplied in PBS, pH-7.4, and 10%
Glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Biological Activity
/
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Synonyms
Ovasin, PRSS19, TADG14, NRPN, NP, Kallikrein 8
(Neuropsin/Ovasin) 2 EC 3.4.21.118, Kallikrein-8, Neuropsin, EC 3.4.21 61,
HNP, HK8
Amino acid sequence
QGSKILEGRE CIPHSQPWQA ALFQGERLIC GGVLVGDRWV LTAAHCKKQK YSVRLGDHSL QSRDQPEQEI QVAQSIQHPC YNNSNPEDHS HDIMLIRLQN SANLGDKVKP VQLANLCPKV GQKCIISGWG TVTSPQENFP NTLNCAEVKI YSQNKCERAY PGKITEGMVC AGSSNGADTC QGDSGGPLVC DGMLQGITSW GSDPCGKPEK PGVYTKICRY TTWIKKTMDN RD LEHHHHHH .
Background
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