Name
PAP Human
Cat. No.
MAG-3604
Tag/Conjugates
His
Source
Pooled human seminal fluid.
Shipped
At Room Temperature
Description
Human Prostate Acid Phosphatase produced in Pooled human seminal fluid having a molecular mass of approximately 100kD.
Introduction
Prostatic acid phosphatase, also known as PAP, is an enzyme produced by the prostate. PAP may be found in increased amounts in men with prostate cancer. PAP’s physiological function may be associated with the liquefaction process of semen. The highest levels of PAP are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells (sickle-cell disease) or multiple myeloma or lysosomal storage diseases (Gaucher's disease), will show moderately higher levels. Certain medications can cause temporary changes in PAP levels. Manipulation of the prostate gland through rectal exam, biopsy or massage may increase the level.
Purification Method
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Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
PAP Human is lyophilized (0.2 µm filtered) from 0.02M NH 4 HCO 3.
Stability
PAP Human although stable at room temperature for 3 weeks, should be stored between 2-8 ° C.
Purity
Greater than 96.0% as determined by SDS-PAGE.
Biological Activity
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Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Synonyms
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Amino acid sequence
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Background
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