Name
CS Human
Cat. No.
MAG-3901
Tag/Conjugates
His
Source
Escherichia Coli.
Shipped
Shipped with Ice Packs
Description
CS Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 462 amino acids (28-466 a.a) and having a molecular mass of 51.4kDa.
Introduction
Citrate synthase also known as CS is a Krebs tricarboxylic acid cycle
enzyme which catalyzes the synthesis of citrate from oxaloacetate and acetyl
coenzyme A. CS is present in almost all cells capable of oxidative metabolism.
CS is nuclear encoded and transported into the mitochondrial matrix, where the
mature form is found. The diseases related to CS are: critical illness
polyneuropathy and mitochondrial cardiomyopathy.
Purification Method
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Physical Appearance
Sterile Filtered colorless solution.
Formulation
CS protein solution (1mg/ml) containing 20mM Tris-HCl
buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Biological Activity
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Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Synonyms
Citrate Synthase, EC 2.3.3.1, Citrate (Si)-Synthase, EC
2.3.3, Citrate synthase, mitochondrial.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGS ASSTNLK DILADLIPKE QARIKTFRQQ HGKTVVGQIT VDMMYGGMRG
MKGLVYETSV LDPDEGIRFR GFSIPECQKL LPKAKGGEEP LPEGLFWLLV TGHIPTEEQV SWLSKEWAKR
AALPSHVVTM LDNFPTNLHP MSQLSAAVTA LNSESNFARA YAQGISRTKY WELIYEDSMD LIAKLPCVAA KIYRNLYREG SGIGAIDSNL
DWSHNFTNML GYTDHQFTEL TRLYLTIHSD HEGGNVSAHT SHLVGSALSD PYLSFAAAMN GLAGPLHGLA
NQEVLVWLTQ LQKEVGKDVS DEKLRDYIWN TLNSGRVVPG YGHAVLRKTD PRYTCQREFA LKHLPNDPMF KLVAQLYKIV PNVLLEQGKA KNPWPNVDAH SGVLLQYYGM
TEMNYYTVLF GVSRALGVLA QLIWSRALGF PLERPKSMST EGLMKFVDSK SG.
Background
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