Cat. No.
MABL-3820
Application
ELISA, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
H18A
From
Recombinant Antibody
Specificity
Alternative Names
Lewis Y
UniProt
Immunogen
Lewis Y.
Application Notes
The antibody binds specifically to LeY tetrasaccharide, a carbohydrate antigen expressed at the cell surface of selective carcinomas, including those of the colon, breast, ovary and lung. The monoclonal antibody may be of clinical use for the in vivo diagnosis and therapy of certain cancers.
Antibody First Published
Kaneko T, Iba Y, Zenita K, Shigeta K, Nakano K, Ito W, Kurosawa Y, Kannagi R, Yasukawa K. Preparation of mouse-human chimeric antibody to an embryonic carbohydrate antigen, Lewis Y. J Biochem. 1993 Jan;113(1):114-7. PMID:8095932
Note on publication
Describes the generation and sequence analysis of the monoclonal antibody H18A, directed against Lewis Y antigen. A chimeric version of the antibody is also produced.
Size
301 μg Purified antibody.
Concentration
202 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 501.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 221⁰C.