Cat. No.
MABL-3857
Application
IP, WB, ELISA, FC, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
2D10
From
Recombinant Antibody
Specificity
Recognises human Vascular Adhesion Protein-1 (VAP-1), a glycosylated homodimeric membrane protein consisting of two 90 kDa subunits connected by disulfide bonds. 2D10 is a conformational specific antibody which recognizes an epitope present only in the dimeric form of VAP-1. Elevated soluble VAP-1 serum- levels have been described in several inflammatory- diseases as well as colorectal cancer.
Alternative Names
Vascular adhesion protein 1; VAP1; Copper amine oxidase; HPAO; Membrane primary amine oxidase; Semicarbazide-sensitive; AOC3; Amine oxidase, copper containing 3; amine oxidase; amine oxidase; Vascular adhesion protein 1; SSAO; copper-containing amine
UniProt
Q16853
Immunogen
Affinity purified VAP-1 from tonsil stroma of human origin.
Application Notes
Antibody First Published
Kurkijärvi R, Adams DH, Leino R, Möttönen T, Jalkanen S, Salmi M. Circulating form of human vascular adhesion protein-1 (VAP-1): increased serum levels in inflammatory liver diseases. J Immunol. 1998 Aug 1;161(3):1549-57. PMID:9686623
Note on publication
Describes the production of monoclonal antibody against VAP-1 (2D10) and its use in immunoblotting to identify that circulating soluble VAP-1 in serum exists primarily as a dimer.
Size
338 μg Purified antibody.
Concentration
239 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 538.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 258⁰C.
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